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The synergy between exogenous MOTS-c and exercise is not merely additive: because MOTS-c mimics one of the molecular consequences of high-intensity exercise (AMPK activation via AICAR accumulation), concurrent exercise training may amplify the peptide's effects on GLUT4 translocation and mitochondrial biogenesis
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(3) V Susi, G Masirevi, and S Toti (1987) The effects of delta-sleep-inducing peptide (DSIP) on wakefulness and sleep patterns in the cat Brain Research, 1987 Jun 30, Volume 414 (Issue 2), Pages 262-70
Journal of applied physiology
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