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Again, if there is an unexpected result, it is useful to repeat the test
FDA's 2024 review states the mechanism of action is still unknown, which limits how confidently any specific physiological effect can be predicted in humans
Although we cannot rule out that the increased production of ROS in 3D culture conditions may not be observed under hypoxia, it should be noted that hypoxia itself induces ROS production in numerous cell types, including tumor cells [39]
And vice versa: The weaker the acid, the stronger its conjugate base
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