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People with a personal or family history of thyroid cancer should not take semaglutide, and this may apply to retatrutide as well, pending FDA review

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GLP-1 Drugs Have Changed Obesity Treatment, But Many Stop Taking Them Newer weight loss medications, including glucagon-like peptide-1 (GLP-1) receptor agonists such as semaglutide (Ozempic, Wegovy, and Rybelsus) and tirzepatide (Mounjaro and Zepbound), have significantly reshaped obesity treatment by helping many patients lose substantial amounts of weight

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