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David: Exactly, and its no coincidence

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The HPA axis controls stress hormone release, such as cortisol, from the adrenal glands

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However, both injection and oral routes produce similar GI symptom duration overall because the receptor activation (subsequent adaptation) occurs in the brain and digestive tract regardless of entry route

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August 2023: Pharmaphorum article, August 2023: 7 2024: The obesity markets inflection point

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