Glutathione may help address hyperpigmentation and uneven skin tone by inhibiting melanin synthesis, providing antioxidant protection, detoxifying and improving skin clarity, increasing skin brightness, supporting collagen production, and improving skin texture
in a more recent nationwide population-based study, showed a similar outcome in 19,397 adults with IDA and 38,794 controls, with a higher incidence of anxiety disorders, depression, sleep disorders, and psychotic disorders in those with IDA
NPI-002 has demonstrated activity against peroxide- and glucose oxidase-induced cataracts in isolated rat and pig lenses
However, for more advanced outcomes such as skin whitening, liver detoxification, or anti-aging effects , higher doses delivered via IV therapy or injection are often necessary ranging from 600 mg to 2400 mg per session , depending on body weight and treatment goals