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Are New Statins Born

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Tolerability and side effects : Starting at a lower dose and increasing gradually helps minimize potential side effects

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2010;362(18):16751685 Hoofnagle JH, Van Natta ML, Kleiner DE, Clark JM, Kowdley KV, Loomba R, et al

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In mitochondria, lipid oxidation causes loss of membrane potential, increases reactive oxygen species (ROS) and promotes epithelialmesenchymal transition (EMT) (Wang et al., 2016

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