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These signals may indicate dwindling antioxidant levels, depleted energy stores, and a lack of essential nutrients
Physically active individuals often generate increased oxidative stress through repetitive muscle contraction, tissue microtrauma, and elevated metabolic demand
While multiple advantageous aspects of the metabolic reprogramming for NRF2-addicted cancer cells have been described, metabolic liabilities resulting from NRF2-dependent reprogramming have also been investigated
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