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For obesity indications, weight loss of at least 5% from baseline is typical

Safety and efficacy of oral semaglutide versus dulaglutide both in combination with one OAD (oral antidiabetic drug) in Japanese subjects with type 2 diabetes (PIONEER10)

Although well tolerated by most individuals, it can worsen symptoms in patients with underlying cardiovascular instability

De Araujo is finding that adverse reactions might be caused by how the drug differs from the naturally occurring peptide hormone: The hormone acts mostly locally and degrades quickly, while the medicine works mainly on the brain and is designed to stick around in the body