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Discussion Across rodent and cell models, NNMT inhibition acts as a metabolic re-allocator, simultaneously relieving a methyl sink and diverting nicotinamide back to NAD salvage
doi: 10.1073/pnas.94.22.12128 97 KaplanMMuracaMVremanHJHammermanCVileiMTRubaltelliFFet al
The technique is essentially identical to that used for subcutaneous insulin administration, and most patients familiar with other injectable medications adapt quickly
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