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As evidence mounts, pharmaceutical stakeholders highlight its significance in chronic weight management

Reviewing the body of evidence to date, Brown noted that these drugs appear to significantly improve inflammation even before people lose much weight, possibly due to a direct effect on T-cells

Any future oral formulation would likely share similar systemic effects, though the gastrointestinal profile might differ

GSK is paying $500 million upfront to get the ball rolling on the alliance, claiming rights to the first programme, a PDE3/4 inhibitor codenamed HRS-9821 in clinical development for the treatment of chronic obstructive pulmonary disease (COPD), outside China and some of its territories