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The Limitations of Traditional Melasma Treatments Conventional approaches to treating melasma have included: Topical agents (hydroquinone, retinoids, corticosteroids) Chemical peels Conventional laser therapies Oral medications Lifestyle modifications Sun protection measures While these methods can offer some improvement, they often fall short of delivering comprehensive, long-lasting results

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The participants were enrolled at the sites of sample collection, as detailed in the ESM INNODIA Project Overview and ESM Table 3

Safety and Things to Consider safety-and-things-to-consider Both Cinderella IV and Glutathione are considered safe when administered under medical supervision, but like any treatment, they are not one-size-fits-all