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As people age, they sometimes have trouble absorbing vitamin B12, even when taking pills by mouth, which is when vitamin B12 injections may be considered
User 13, at 280 pounds, specifically questioned whether his 0.25mg subcutaneous dose was insufficient given his body weight
Some chemotherapy drugs or antiretroviral medications (for HIV) that suppress bone marrow might also blunt the effectiveness of B therapy
Caution applies for individuals with cardiovascular conditions, though topical application minimizes systemic exposure
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