As a persons heart rate slows, oxygen levels may fall low enough that the heart starts having abnormal rhythms and is not functioning properly
Specifically, pigs and ferrets are considered high-fidelity models because of their lung anatomy, physiology, and pathology (including spontaneous bacterial infections, inflammation, and mucus plugging) closely recapitulate the human CF condition from birth
Sandor PS, Di Clemente L, Coppola G, Saenger U, Fumal A, Magis D, et al
However, other study reported that NKT cells-deficient mice (DC1d / and J18 / mice) show more susceptibility to AILI since starved NKT cells-deficient mice produce more ketone bodies, which up-regulate expression of CYP2E1 [105]