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Vallance HD, Koochin A, Branov J, Rosen-Heath A, Bosdet T, Wang Z, Hazen SL, Horvath G

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After the plasma membrane carrier-mediated GSH release from the cell, GSH becomes accessible to the active site of - glutamyl transpeptidase, which catalyzes the breakdown of the GSH - glutamyl bond forming two fractions: The -glutamyl fraction and the cysteinyl-glycine by transferring the -glutamyl fraction to an amino acid acceptor, forming -glutamyl-amino acid

We also analysed whether persistent GLP-1RA users experienced fewer cardiovascular outcomes and lower all-cause mortality than non-persistent patients