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A potential longer-term impact may be a change in claims cause trends for critical illness claims
In the STEP-4 randomized trial (Rubino and colleagues, JAMA, 2021), the 803 adults who switched to placebo at week 20 regained about 6.9 percent of body weight over the next 48 weeks, while those who continued semaglutide kept losing
This adjustment period can trigger nausea as your digestive system adapts to these new chemical messages
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