In contrast those losing weight through diet and exercise alone only saw a reduction of 3% over that time period, the same study found
Immediate Management If hypoglycaemia occurs: Break the fast immediately this is medically necessary Have 15-20g fast-acting carbohydrates: 3-5 dates 120ml fruit juice 3-4 glucose tablets Wait 15 minutes and reassess symptoms If symptoms persist: Have another 15-20g carbs and seek medical attention Prevention Strategies Ensure adequate complex carbohydrate intake at Suhoor (covered in Part 2) Never skip Suhoor this is critical when on GLP-1s Monitor symptoms closely, especially in Week 1 of Ramadan Consider dose reduction if on higher doses (Mounjaro 10mg+, Wegovy 1.7mg+) Keep glucose tablets handy if on higher doses Important: The risk is LOW in non-diabetic patients, but being prepared is essential
In summary, combination therapy produced consistent and clinically meaningful reductions in HbA1c, averaging about 0.71.3% compared with monotherapy or placebo
The gastrointestinal tract and the brain are involved in a complex bidirectional communication, which is mediated by the endocrine, immune and neural pathways, involving a plethora of different neurotransmitters, cytokines and peptide hormones [98]
