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When stress persists, the -cell gradually retreats and converts into a dedifferentiated pancreatic progenitor, which might be more resistant to high-glucose/ROS challenges 22,29 and thus survives

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While glycine is classified as a non-essential amino acid (meaning the body can synthesize it), multiple studies suggest that endogenous production does not meet human metabolic demands, especially during periods of growth, stress (including intense exercise), aging, or injury