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GIPRs have been localized to human pancreatic -cells, and intravenous GIP infusion activates GIPR and intracellular signaling in pancreatic -cells, augmenting glucagonotropic effects in hypoglycemic conditions in humans (130)

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Discontinuation due to side effects typically ranges 26% across agents, suggesting most adverse events are manageable rather than prohibitive

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doi: 10.1016/S2213-2600(19)30198-5, 2

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In the weeks leading up to Thanksgiving, Ive stressed over how much Id end up eating and if Id be able to grapple with not overeating (even by Thanksgiving standards)

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