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Key Safety Differentiators No IGF-1 elevation: AOD-9604 does not stimulate IGF-1, meaning it avoids risks such as organ/tissue overgrowth or acromegaly No glucose disruption: Clinical data shows it does not impair insulin sensitivity or worsen blood sugar regulation Comparable to placebo: In obesity trials, the incidence of adverse effects was similar to placebo groups, underscoring its tolerability Legal Status of AOD-9604 United States: AOD-9604 is not FDA-approved as a drug, dietary supplement, or weight loss therapy

Protection of the Gastrointestinal Tract : BPC-157 has demonstrated protective effects in experimental models of gastric ulcers, intestinal inflammation, and colitis

"There is no other drug on the market that had that sort of safety record," Tatem said

Side effects and tolerability CagriSemas side-effect profile in REDEFINE 1 was similar in pattern to Wegovy and Mounjaro