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Individual variability is significant and depends on starting weight, metabolic factors, medication adherence, dose optimization, lifestyle factors, and genetic variables

In the Phase 1b trial of higher doses (9 mg and 10 mg), 95% of participants experienced at least one adverse event, but only one participant discontinued treatment due to side effects

Phase 2 trial data (NEJM, 2023) showed substantial MRI-PDFF-measured liver fat reductions at 8 mg and 12 mg weekly doses, with some participants falling below the 5% hepatic steatosis threshold

Today, research supports many of the potential benefits of spirulina, and researchers continue to study its potential for treating health concerns