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The enzyme methionine synthase needs methylcobalamin as a cofactor
Optic nerve atrophy can worsen in patients whose methylcobalamin levels are already elevated
It is used to treat or prevent vitamin B12 deficiency caused by conditions such as pernicious anemia, low dietary intake, certain gastrointestinal disorders, or surgeries that reduce absorption
During rapid correction of severe anemia, potassium may need monitoring in some higher-risk patients
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