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Perfect B is currently evaluating AOD 9604 internally and does not yet offer it to patients

IC50 can change with enzyme source, substrate and SAM concentrations, buffer, temperature, readout, and compound form

Molecular Basis of Local Action The local effect of AOD 9604 injection is closely related to its molecular properties: Receptor specificity AOD 9604 has a high affinity for 3-AR and reduces systemic side effects

A 2025 JAMA Neurology trial (n=1,500, aged 50-70) reported a 10-15% reduction in amyloid-beta plaques in mild cognitive impairment (MCI) patients receiving 1,000 mcg weekly, slowing progression to dementia by 12-18%