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As a result, most people likely see weight regain, even in the setting of continuing the lifestyle recommendations such as creating caloric deficit with diet and exercise, says Lofton

For someone with a functional gastrointestinal disorder like IBS, these signals can either be a source of relief or a potential trigger for discomfort, depending on their specific symptoms

Her framing aligns with the mechanistic literature, though she is careful to note the absence of long-term human outcome data

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