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Preclinical Onset Data (Animal Models Not a Human Timeline) The cleanest independent support for Dihexa is a 2021 study from a Chinese group (Sun et al., Brain Sciences, PMID 34827486) in APP/PS1 Alzheimer's-model mice

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Finally, the integration of multi-omics datasets with the development of associated computational and functional validation platforms poses a technological challenge, for which systems-based approaches in the development of precision therapy and precision medicine are required (330)