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In a study by Ji et al., a novel group of -amino pyrrole-2-carbonitrile analogs was developed as selective DPP-4 inhibitors, with compound 55 (Figure 7) identified as the most potent, exhibiting an IC 50 value of 0.01 M
For instance, the SKSC222 strain, engineered with a synthetic isozyme system, achieved 2.0 g/L of glutathione with a volumetric productivity of 29.85 mg/L/h under fed-batch fermentation conditions (Jeon et al., 2023)
P.AltieriN.AlvarezJ.GreenJ.HinchliffeJ.et al (2020)
Fortunately, this is not the case, or at least it is up for debate
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