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8 Nitric oxide (NO) normally activates soluble guanylate cyclase, to act as a neurotransmitter and blood pressure regulator
Peer review Peer review information Nature Medicine thanks John Wilding and the other, anonymous, reviewer(s) for their contribution to the peer review of this work
Another key aspect frequently reported in the literature is increased oxidative stress, which may play a role in the pathophysiology of PKU (Dobrowolski et al., 2022
The most common side effects are gastrointestinal, including nausea, vomiting, diarrhoea, and decreased appetite
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