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Mechanism of action Inhibits nicotinamide N-methyltransferase, raising NAD+ pools
GLP-1s trigger insulin secretion when food is eaten, helping to lower blood glucose levels
These hormones help regulate blood sugar, slow digestion, reduce appetite, and promote a feeling of fullness, supporting both improved metabolic control and sustained weight loss
In addition, a dual GLP-1/glucose-dependent insulinotropic polypeptide (GIP) co-agonist, tirzepatide, has been recently developed for the treatment of type 2 diabetes and obesity (Jakubowska et al., 2024)
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