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A second-generation glucagon-like peptide-1 receptor agonist mitigates vomiting and anorexia while retaining glucoregulatory potency in lean diabetic and emetic mammalian models
3.6 Determination of urine TMA levels in C57Bl/6-Fmo3 em1smoc mice TMA levels were evaluated in urine collected from C57Bl/6-Fmo3 em1smoc mice, which lack the Fmo3 enzyme responsible for the conversion of TMA to TMAO
For drug developers watching the GLP-1 space, RJVA-001 represents an early but notable test of whether gene therapy can move from managing metabolic disease to potentially treating it once
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