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Symptoms typically emerge during dose titration and often diminish over several weeks, though some individuals experience persistent gastrointestinal upset requiring dose adjustment or discontinuation
While these drugs have benefits, there is a serious risk of low blood sugar for those with type 1 diabetes who take a GLP-1 agonist together with insulin
That long duration is one of the underlying reasons semaglutide is weekly rather than daily
MACEs, major adverse cardiac events
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