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Chronic GLP-1 Receptor Activation by Exendin-4 Induces Expansion of Pancreatic Duct Glands in Rats and Accelerates Formation of Dysplastic Lesions and Chronic Pancreatitis in the Kras(G12D) Mouse Model

Early data from metagenomic analyses of GLP-1 RA users suggest that semaglutide alters bacterial composition in ways that may increase short-chain fatty acid production and osmotic load in the colon

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The most common ones include: Semaglutide (brand names Ozempic and Wegovy) Tirzepatide (brand names Mounjaro and Zepbound) Liraglutide (brand name Victoza) These medications were first created to help people with type 2 diabetes