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Zhao B, Geisslinger G, Hall I, Day RO, Williams KM (1992) The effect of the enantiomers of ibuprofen and flurbiprofen on the beta-oxidation of palmitate in the rat

found that signal transducers and activators of transcription 3 (STAT3) promote MYC expression in tumor cells in AML, which in turn regulates the transcription of amino acid transporter SLC1A5, promotes Gln metabolism in AML cells, and oxidative phosphorylation (OXPHOS) of leukemia stem cells (LSCs)

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