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In clinical trials, participants were assigned to specific dose groups and followed set escalation schedules

In AD, A damages microglia, produces inflammatory cytokines and chemokines, and affects surrounding CNS resident cells (astrocytes, oligodendrocytes, and neurons), which may aggravate tau pathology and ultimately lead to neurodegeneration and neuron loss

We need to ensure that reproductive health is part of every conversation when these drugs are prescribed to any women of childbearing age

It raises interesting questions around whether future strategies could further optimize outcomes through combination approaches or more targeted pathway modulation