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Abbreviations AA: Amino acid [Ca 2+ ] i : Cytoplasmic free Ca 2+ concentration DPP-4: Dipeptidyl peptidase 4 EGFP: Enhanced green fluorescent protein GCGR: Glucagon receptor GLP-1: Glucagon-like peptide 1 GLP-1R: GLP-1 receptor GPCR: G protein-coupled receptor GRA: Glucagon receptor antagonist IC 50 : Half-maximal inhibitory concentration NPY: Neuropeptide Y PKA: Protein kinase A PPPG: Preproglucagon promoter P/Q-type Ca 2+ channel: Voltage-gated Ca 2+ channel sensitive to -agatoxin PTX: Pertussis toxin TIRF (microscopy): Total internal reflection fluorescence (microscopy) VGCC: Voltage-gated calcium channel References Cryer PE (2015) Hypoglycemia-associated autonomic failure in diabetes: maladaptive, adaptive, or both
Friedman SD et al., "Growth hormone-releasing hormone effects on brain gamma-aminobutyric acid levels in mild cognitive impairment and healthy aging," JAMA Neurology, 2013
Compounded drugs aren't tested or approved by the US Food and Drug Administration, so there's no guarantee they're safe or that they work
In critically-ill patients, supplements improved nutritional status indicators, which have a key role in prognosis of diseases (64) and adjunctive use improved symptoms of autism spectrum disorder in children and adolescents (65)
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