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And since then weve gone absolute gangbusters, with listings in Sprouts, Erewhon and Bristol Farms and other significant retail launches coming up as well. Unusually for a brand of this size, Washington also has a human clinical study showing volunteers with type 2 diabetes consuming Supergut products demonstrated improved glycemic control and a small reduction in body weight in a 12-week study
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Tirzepatide: A Direct Comparison No large head-to-head randomized controlled trial comparing semaglutide 2.4 mg (Wegovy) to tirzepatide 15 mg (Zepbound) for weight loss has been published as of early 2025, so cross-trial comparisons carry significant limitations
The bigger picture: endometriosis and metabolic health The GLP-1 and endometriosis connection is part of a larger scientific shift toward understanding endometriosis as a systemic metabolic and inflammatory disease rather than a purely reproductive condition
TRIUMPH-1 (80 Weeks) The pivotal TRIUMPH-1 obesity trial (2,339 adults, no diabetes), presented at ADA 2026, extended the treatment window to 80 weeks and produced the largest pivotal weight-loss readout to date: Among the 12 mg group, 45.3% lost at least 30% of their body weight and 65.3% ended the trial with a BMI below 30
