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But if you come back every week for a month or so you'll notice a big difference in your overall level of energy." So the very first time someone gets a B12 shot they probably won't feel much of an effect, even though they might experience a bit of an energy boost after the very first one, but it usually only lasts for about a week
Another trial in 54 individuals confirmed its safety over 10 days of intravenous use at doses of up to 5.0g/kg (and up to 25.0g/kg in a single-dose trial)
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