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One study showed that people with depression had on average a lower ALCAR levels

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Studies have also shown that these drugs interact with other parts of the body, potentially reducing the risk of health conditions such as kidney disease, cardiovascular diseases, and heart attacks

These findings underscore the critical need for physicians to thoroughly assess patient history before prescribing GLP-1 RAs and highlight the urgent requirement for further prospective clinical trials to fully understand the implications of GLP-1 RA use on mental health in the obese patient population