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1,2 While the primary endpoint in the majority of clinical trials was mean change in A1C, mean change in body weight was generally evaluated as a confirmatory secondary endpoint
This study was small and has not been replicated
ROS production and associated inflammation are closely related to aging and numerous chronic diseases as diabetes, cardiovascular and respiratory diseases, known risk factors for developing severe illness and death in patients with SARS-CoV-2 and COVID-19 disease
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