Once reconstituted with bacteriostatic water or saline, NAD+ degrades rapidly at room temperature due to enzymatic hydrolysis and must be refrigerated at 28C and used within 28 days
Over time, this can contribute to gaps in protein, hydration, vitamins, and minerals that may affect energy, muscle maintenance, hair health, digestion, and overall daily balance
Tricyclic antidepressants, such as cyclobenzaprine are dosed at 520 mg or nortriptyline, initiated at a dose of 10 mg at bedtime, while SNRIs like duloxetine and venlafaxine are started at 30 mg and 37.5 mg daily, respectively, titrated to a maximum of 50% of that used in non-cirrhotic population
Do not attempt to self-treat cardiac symptoms with supplements alone