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Its interaction with dopamine signaling is the central pharmacodynamic concern when combining it with amphetamine-based medications
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We confirmed that all of the PSCs in both quiescent and activated state expressed GLP-1R with nuclear staining (Supplementary Figure S1)
At the same time, GLP-1s are now understood to have potent anti-inflammatory effects in the brain that could reduce depression for individuals with depression related to inflammation
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