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Evolutionary aspects of cellular communication in the vertebrate hypothalamo-hypophysio-gonadal axis

GrimAge V1 and V2 were computed using the Biolearn Python library ( OMICmAge was calculated using code available at CausAge, DamAge, and AdaptAge were calculated using algorithms available in the Supplementary Information of the original publication and via the ClockBase platform (www.clockbase.org) and the Biolearn Python package ( RetroAge was calculated using retroelement-based clock coefficients and scripts deposited on Zenodo (DOI: 10.5281/zenodo.11099870), which support DNA methylation EPIC v1.0 and v2.0 datasets