It is one of the major inhibitory neurotransmitters in the spinal cord and brainstem, akin to -aminobutyric acid (GABA)
Curr Opin Infect Dis 28:1722 Winston A, Duncombe C, Li PC, Gill JM, Kerr SJ, Puls R, Petoumenos K, Taylor-Robinson SD, Emery S, Cooper DA, Altair Study G (2010) Does choice of combination antiretroviral therapy (cART) alter changes in cerebral function testing after 48 weeks in treatment-naive, HIV-1-infected individuals commencing cART
Insufficient glucocorticoid receptor signaling and flattened salivary cortisol profile are associated with metabolic and inflammatory indices in type 2 diabetes
Conservative approaches start at 0.2-0.25 mg, while acute injuries may warrant 0.5-0.75 mg daily split into two doses