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Nuclear factor-kappa B (NF-B) is a transcription factor that binds DNA and induces the transcription of the COX-2 gene, other pro-inflammatory genes, as well as genes involved in cell proliferation, adhesion, survival, and differentiation

Appetite suppression typically becomes stronger

However, if serum cobalamin concentration is within the normal range, treatment should be continued at least monthly (for parenteral supplementation) and the owner should be forewarned that clinical signs may recur sometime in the future

The salary of MS is supported by a Royal Perth Hospital Research Foundation Career Advancement Fellowship (ID: 00/2020)