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Contact your GP or prescribing clinician if: Your constipation has not improved after trying self-care measures and over-the-counter laxatives for around 3 weeks You have abdominal pain : Particularly if it's persistent, worsening, or accompanied by distension You experience nausea and vomiting : Especially if persistent or preventing adequate fluid intake You notice blood in stools : Either bright red blood or black, tarry stools You have unexplained weight loss : Beyond what is expected from the treatment programme You develop a fever : Which may indicate infection or inflammation Contact NHS 111 or seek urgent medical attention if: Your symptoms are severe or getting worse rapidly You're unable to keep fluids down You have signs of dehydration (dizziness, reduced urination, confusion) Seek emergency medical attention (A&E or call 999) if you develop: Severe, sudden abdominal pain with rigidity Inability to pass wind or stools with progressive abdominal distension Persistent vomiting preventing fluid intake Severe dehydration or confusion Patients and healthcare professionals can report suspected side effects of medications through the MHRA Yellow Card scheme
High cholesterol High levels of low-density lipoprotein (LDL) cholesterol and triglycerides A 2021 systematic review highlights research suggesting that berberine may help lower LDL cholesterol and triglyceride levels
Allow the cream to fully absorb before applying any additional products or going to bed
For vegetarians and those who avoid red meat, along with those genetically predisposed to not using certain fats for energy, it can be easy to grow deficient in carnitine
