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US26SEMO01369 June 2026
A rational multi-receptor design is a hypothesis to be tested, not an outcome to be assumed and the balance between glucagon's metabolic upside and its capacity to raise glucose is precisely the kind of question that careful clinical trials exist to resolve
DPP-4 inhibitors can on the other hand also be combined with an oral therapy with a SGLT-2 inhibitor (in dual combination when metformin is contraindicated or not tolerated or in triple therapy with metformin)
The acquisition provided Roche with three clinical-stage assets with potential in treating obesity and diabetes
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