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Concurrent GH secretagogue and IGF1R agonist research uses compounds like CJC-1295/Ipamorelin alongside IGF-1 LR3 to study whether pulsatile endogenous GH/IGF-1 release combined with sustained IGF1R activation produces additive or synergistic effects on muscle, bone, or other target tissues

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The Extended 20-Day Protocol Some practitioners recommend a longer cycle for potentially enhanced benefits: Daily dose : 5-10mg Duration : 20 consecutive days Total per cycle : 100-200mg Frequency : 1-2 times per year This extended protocol may be particularly suitable for older individuals or those seeking more pronounced effects on biological aging markers