pioneer 7 semaglutide Efficacy and safety of oral semaglutide with flexible dose adjustment versus sitagliptin in type 2 diabetes (PIONEER 7): a multicentre, open-label, randomised, phase 3a trial PDF) Long-term efficacy and safety

Retatrutides Phase 2 data suggest that the addition of a third receptor target may extend the efficacy ceiling further still, though direct head-to-head trials would be needed to draw firm comparative conclusions

Link: Gomes, A

Acquisitions are adding further pipeline depth and long-term optionality

Department of Periodontology and Oral Medicine, University of Limpopo, Medunsa Campus, South Africa ACRONYMS aMSH: alpha melanocyte stimulating hormone HAART: highly active antiretroviral therapy MC1R: melanocortin 1 receptor OMH: Oral melanin hyperpigmentation HIV-OMH: HIV associated oral melanin hyperpigmentation INTRODUCTION Oral melanin hyperpigmentation (OMH) is not uncommon in HIV+ persons 1 In Venezuela (38%) 5 and in India (30%) 3 HIV-associated OMH (HIV-OMH) is quite common, but by contrast is substantially less common in Italy (6.4%) 4 and in sub-Saharan Africa (Tanzania, 4.7%, Kenya, 6%)