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Bone fractures : Clinical trial data suggest a possible increased risk of bone fractures with canagliflozin, particularly in the first year of treatment
Effectiveness questions naturally arise when comparing different administration methods for identical pharmaceutical compounds and active ingredients used in treatment
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Other At-Risk Groups GLP-1 medications are generally not suitable for individuals with severe gastrointestinal disorders like gastroparesis, those with type 1 diabetes (as these drugs are approved only for type 2 diabetes and obesity), and people with a history of suicidal thoughts, active eating disorders, or heavy alcohol use
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