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Trends Microbiol
(1) Stimulate chondrocytes to synthesize Col-II and proteoglycans, while inhibiting the activities of MMP-13 and ADAMTS-5, and reducing matrix degradation
These GLP-1 receptor agonists can be categorized as either short-acting compounds, which provide short-lived receptor activation (such as exenatide and lixisenatide) or as long-acting compounds (for example albiglutide, dulaglutide, exenatide long-acting release, and liraglutide), which activate the GLP-1 receptor continuously at their recommended dose
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