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GLP-1 receptor agonists available in the UK include: Semaglutide (Ozempic, Wegovy, Rybelsus) - Ozempic and Rybelsus for diabetes, Wegovy for weight management Dulaglutide (Trulicity) Liraglutide (Victoza, Saxenda) - Victoza for diabetes, Saxenda for weight management Lixisenatide (Lyxumia) Exenatide (Byetta, Bydureon) - though usage has declined in recent years These medications are administered either as once-daily, once-weekly, or twice-daily subcutaneous injections, with one oral formulation (semaglutide) also available

As we age, these "springs" can appear weaker, leading to skin that doesn't bounce back like it used to

Persistent neurological symptoms, fatigue, or symptom recurrence before scheduled injections warrant medical review and possible dosage adjustment

"Perhaps doses that achieve modest weight loss but robust anti-inflammatory and vascular benefits might be appropriate for some indications, while maximum-tolerated doses remain appropriate for obesity," says Nadolsky