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Developed by Eli Lilly, it is a single-molecule triple receptor agonist targeting three key metabolic hormone receptors simultaneously: GLP-1 (glucagon-like peptide-1), GIP (glucose-dependent insulinotropic polypeptide), and glucagon

This route is particularly relevant for gastrointestinal applications

Phase 2 trial establishing 24.2% mean weight loss at 12mg over 48 weeks, with dose-response data across the 1mg to 12mg range

"Semaglutide has been extensively examined in robust clinical development programs, large real world evidence studies and has cumulatively over 9.5 million patient years of clinical experience," the company says in a statement